Drug resistance is one of the major causes of cancer-related deaths. Here. the authors using single cell RNA-seq of oral squamous cell carcinoma patient samples pre- and post-cisplatin treatment show that phenotypically homogenous cell populations display cell state plasticity. with poised chromatin marks at mesenchymal genes in epithelial cells. https://www.getpureroutine.com/special-pick-aus-309-darwin-to-penguin-shoal-fashion-great-offer/