Pentobarbital will decrease the level or effect of ketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of diclofenac by affecting hepatic enzyme CYP2C9/10 metabolism. Minor/Significance Unknown. pentobarbital will decrease the level or effect of cevimeline by affecting hepatic/intestinal enz... https://admiralbookmarks.com/story20347958/pentobarbital-cosa-%C3%88-una-panoramica