The narcotic antagonist, naloxone hydrochloride, could be administered when substantial respiratory despair happens with promethazine and codeine; any depressant effects of promethazine usually are not reversed with naloxone. Diazepam might be applied to control convulsions. Prevent analeptics, which may result in convulsions. Acidosis and electrolyte losses need to be corrected. https://socialmediatotal.com/story2763351/indicators-on-promethazine-with-codeine-you-should-know