Mesothelioma and Work Exposure Workers who work with asbestos are more at risk of developing mesothelioma. People who work in construction, firefighters or military veterans are particularly at risk. Mesothelioma primarily affects the lung's lining (pleural mesothelioma) or abdomen. In rare cases, it can affect the heart and testicles. Consult https://vimeo.com/705048067