At three days put up-MPTP, we discovered considerable microglial activation and up-regulation of CB2 cannabinoid receptors during the ventral midbrain. Treatment with Acquire or maybe the CB2 receptor agonist JWH015 (four mg/kg, intraperitoneal) lessened MPTP-induced microglial activation, whereas genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. On top of https://win55.clinic/casino