Lifetime-threatening respiratory melancholy and Dying have transpired in little ones who received codeine. The vast majority of claimed situations occurred adhering to tonsillectomy and/or adenoidectomy and several of the kids experienced proof of staying ultra-quick metabolizers of codeine resulting from a cytochrome P450 (CYP) 2D6 polymorphism (see WARNINGS, Safeguards; Information https://wockusa.com/product/actavis-legal-lean/